Mysimba 8 mg/90 mg 112 tablets in Box (naltrexone hydrochloride/bupropion hydrochloride)0 from 5 / 0 Vote
What Mysimba is and what it is used for
Mysimba contains 2 active substances: naltrexone hydrochloride and bupropion hydrochloride and is used in obese or overweight adults to control weight, along with a low calorie diet and exercise. This medicine acts on areas of the brain involved in the control of food intake and energy consumption.
Obesity in adults over 18 years is defined as a body mass index greater than or equal to 30, and overweight in adults over 18 years is defined as a body mass index of greater than or equal to 27 and less than 30. The index of body mass is calculated by dividing the measured body weight (kg) by the measured square height (m2).
Mysimba is authorized for use in patients with baseline body mass index of at least 30; can also be given to people with a body mass index of between 27 and 30 if they have other weight-related conditions such as controlled high blood pressure (hypertension), type 2 diabetes or high blood lipid levels (fats).
The use of Mysimba may be stopped by your doctor after 16 weeks unless you have reduced your body weight by at least 5%. Your doctor may recommend stopping treatment if there is any reason to increase your blood pressure and other concerns about the safety and tolerability of this medicine.
The starting dose is usually one tablet (8 mg naltrexone hydrochloride / 90 mg bupropion hydrochloride) once daily in the morning. The dose is gradually adjusted as follows:
• Week 1: One tablet once a day in the morning
• Week 2: One tablet twice a day, one morning and one evening
• Week 3: Three tablets each day, two in the morning and one evening
• Week 4 and then: Two tablets twice a day, two in the morning and two in the evening
The maximum recommended daily dose of Mysimba is two tablets twice a day.
After 16 weeks and every year after starting treatment, your doctor will decide whether you should continue to take Mysimba.
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